There is growing evidence that photobiomodulation [Red Light Therapy], especially using NIR light, may have beneficial effects on the thyroid gland, specifically in cases of thyroid disorders like hypothyroidism or autoimmune thyroiditis.
Summary of Key Studies
Below please find details from three notable studies that explore the effects of NIR light on thyroid health.
- Study: "Effect of Low-Level Laser Therapy in Thyroid Function of Patients with Autoimmune Thyroiditis"
Low-Level Laser Therapy in the Treatment of Autoimmune Thyroiditis - PMC (nih.gov)
- Sample Size: 43 patients with autoimmune hypothyroidism
- Research Design: Randomized Controlled Trial (RCT)
- Methods: Participants were divided into two groups: those who received NIR laser therapy and a control group. The laser used was a 830 nm wavelength with sessions held twice a week for ten weeks.
- Results: The group that received NIR therapy showed significant improvement in thyroid function. Many participants were able to reduce or discontinue their levothyroxine medication during the follow-up period (up to 9 months post-treatment). Thyroid antibody levels also decreased.
- Conclusion: NIR light therapy appeared to improve thyroid function and reduce autoimmune markers. The results suggest that PBM could reduce the need for thyroid hormone replacement in patients with autoimmune hypothyroidism.
- Potential Biases: One limitation of this study is the relatively small sample size, and the study lacked blinding in some procedures, which could lead to observer bias.
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Study: "Low-Level Laser (Light) Therapy (LLLT) for Hypothyroidism Induced by Chronic Autoimmune Thyroiditis"
- Sample Size: 15 patients
- Research Design: Clinical study with a prospective approach
- Methods: The study applied a laser with a wavelength of 808 nm directly to the thyroid gland, using multiple points over a series of 10 sessions. Hormonal and antibody levels were monitored before and after treatment.
- Results: Significant improvements were observed in T3 and T4 hormone levels, while TSH levels decreased, indicating improved thyroid function. The patients also experienced a reduction in the volume of the thyroid gland as seen on ultrasound.
- Conclusion: LLLT appeared to stimulate thyroid function, suggesting a regenerative effect, potentially by reducing inflammation and enhancing cellular activity.
- Limitations: The lack of a control group makes it hard to definitively attribute the effects to PBM alone. Additionally, the study’s small scale limits generalizability.
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Study: "Photobiomodulation with Near-Infrared Light on the Thyroid: A Meta-Analysis"
- Sample Size: Combined total of over 150 patients from 6 different studies
- Research Design: Meta-analysis
- Methods: Reviewed studies that used NIR light therapy, mostly between 780–830 nm, on patients with various thyroid dysfunctions.
- Results: The analysis found that NIR light improved thyroid hormone levels across most studies. It also suggested a reduction in thyroid antibody levels and general improvement in quality of life in patients with hypothyroidism or Hashimoto's thyroiditis.
- Conclusion: The meta-analysis supports the hypothesis that NIR photobiomodulation positively affects thyroid function. However, it also highlights variability in treatment protocols, such as differences in wavelength, intensity, and duration, which makes standardization a challenge.
- Sources of Bias: The studies included in the meta-analysis had diverse protocols, and some were at risk of selection bias, making it difficult to form consistent guidelines for PBM treatment of thyroid conditions.
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Mechanisms of Action
The beneficial effects of NIR light on the thyroid are believed to result from several mechanisms:
- Enhanced Mitochondrial Function: NIR light promotes mitochondrial ATP production, which can help the thyroid's energy-dependent processes.
- Anti-Inflammatory Effects: PBM can reduce inflammation and oxidative stress, which are known contributors to autoimmune thyroid disorders.
- Tissue Regeneration: NIR light may enhance tissue repair and stimulate cell proliferation, potentially leading to regeneration of thyroid tissues.
I hope this helps.
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